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Mechanisms of Improving Fecal Continence Muscles Motor Function
Sponsor: Medical College of Wisconsin
Summary
The investigators hypothesize that different continence muscles have different fatigue characteristics and fatigue induced by resisted contractions will result in significant increase in contractility of the continence muscles and improvement of fecal incontinence severity.
Official title: Mechanisms of Improving Fecal Continence Muscles Motor Function in Health and Disease
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
340
Start Date
2025-07-15
Completion Date
2030-03-01
Last Updated
2025-10-23
Healthy Volunteers
Yes
Conditions
Interventions
continence muscles resistance device
The c-RED consists of a noncompliant cylindrical balloon (intra-anal balloon) that is connected to a small compliant balloon (external balloon) by a 2 mm diameter tube and a stopcock to allow for air to be filled and sealed in the system. The system is prefilled with air to determine the amount of air needed for a given internal pressure, or desired resistance of the intra-anal balloon. This is determined using a sphygmomanometer gauge in a sealed system.
Locations (1)
Medical College of Wisconsin
Milwaukee, Wisconsin, United States