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Comparison of Efficacy of Oral Amoxicillin Versus Intravenous Ceftriaxone
Sponsor: RESnTEC, Institute of Research
Summary
The efficacy of oral amoxicillin is considered equal to that of ceftriaxone in community-acquired pneumonia among children. Also, there are some factors that contradict the usage of ceftriaxone, like antibiotic resistance, adverse reactions, drug cost, and the and the chances of IV trauma and infection, which is a major problem in developing countries. Therefore, this study was planned to determine the efficacy of oral amoxicillin compared with intravenous (IV) ceftriaxone in the treatment of uncomplicated ceftriaxone in community acquired pneumonia in children less than 5 years of age.
Official title: Efficacy of Oral Amoxicillin in Comparison to Intravenous Ceftriaxone in Treatment of Uncomplicated Community Acquired Pneumonia (Cap) Among Children of Age 2-5 Years of Age
Key Details
Gender
All
Age Range
2 Years - 5 Years
Study Type
INTERVENTIONAL
Enrollment
114
Start Date
2024-10-01
Completion Date
2025-09-30
Last Updated
2024-08-01
Healthy Volunteers
No
Conditions
Interventions
Amoxicillin/CA
Patients will receive IV amoxicillin/CA at a dose of 100 mg per kg per day in 3 divided doses for a maximum period of 7 days.
IV ceftriaxone
Patients will receive IV ceftriaxone at a dose of 75 mg per kg per day in 2 divided doses for a maximum period of 7 days.
Locations (1)
Children Hospital
Lahore, Punjab Province, Pakistan