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The Effect of Therapeutic Exercise on Cartilage Morphology and Physical Function for Individuals at High Risk of Knee Osteoarthritis
Sponsor: Jordan University of Science and Technology
Summary
This randomized controlled trial aims to evaluate the efficacy of progressive resistance exercises (PRE) versus aerobic exercises on cartilage morphology and physical function in patients with degenerative meniscus tears. 54 participants, aged 35-55, will be randomly assigned to one of three groups: PRE, aerobic exercise, or control (standard of care physical and medical therapy). The study will utilize MRI T2 mapping to assess changes in cartilage composition and patient-reported and performance-based measures to evaluate clinical outcomes. This pilot study will also determine the feasibility and issues related to recruitment and retention for a larger trial.
Official title: The Efficacy of Progressive Resistance Exercises Versus Aerobic Exercises on Cartilage Morphology and Physical Function in Patients With Degenerative Meniscus Tear: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
35 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
54
Start Date
2024-01-01
Completion Date
2029-10-01
Last Updated
2024-08-01
Healthy Volunteers
Yes
Conditions
Interventions
Progressive Resistance Exercise (PRE)
A structured exercise regimen focusing on increasing muscular strength and endurance through progressive resistance.
Aerobic Exercise
An exercise program focusing on cardiovascular conditioning using a stationary bike.
Control
A set of general strength and balance exercises that do not target the specific therapeutic goals of the other interventions.
Locations (2)
King Abdullah University Hospital
Ar Ramtha, Jordan
Jordan University of Science and Technology
Irbid, Jordan