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Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures
Sponsor: Loma Linda University
Summary
The goal of this double blinded randomized control trial is to learn if percutaneous cryoablation of traumatic rib fractures improves outcomes. The main questions it aims to answer are: Does percutaneous cryoablation improve short and long term pain scores? Does percutaneous cryoablation improve short and long term respiratory mechanics? Does percutaneous cryoablation improve long term quality of life? Does percutaneous cryoablation decrease delirium? Researchers will compare cryoablation to standard multimodal pain therapy to see if this impacts respiratory recovery. Participants will undergo randomization, percutaneous cryoablative procedure, and participate in tests at pre-determined intervals to evaluate their pulmonary recovery.
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-09
Completion Date
2028-07
Last Updated
2026-02-09
Healthy Volunteers
Yes
Conditions
Interventions
Percutaneous Cryoablation of Intercostal Nerves
Percutaneous Cryoablation of Intercostal Nerves
Multi-modal pain regimen
Standard rib fracture protocol including cyclooxygenase inhibitors, anti-neuropathic, muscle relaxers, short term anesthesia interventions (percutaneous block, epidural)
Locations (1)
Loma Linda University Health
Loma Linda, California, United States