Clinical Research Directory

Inclusion Criteria: * The patients voluntarily participate in the study, have good compliance, can cooperate with the requirements of the experiment to complete the observation and follow-up, and sign the informed consent form. * Aged over 18 years old, under 75 years old; male and female are not limited; * Pathologically confirmed non-small cell lung cancer with clinical stage T2-4N0-2, resectable non-small cell lung cancer, potentially needing pneumonectomy and receiving neoadjuvant or induction therapy. * ASA score: Grade I-III; * The cardiopulmonary function evaluation can meet the requirements for radical lung cancer surgery, and the liver and kidney functions are normal. Exclusion Criteria: * Those with serious cardiac, pulmonary, hepatic, and renal dysfunctions, unable to tolerate the surgery; * Those with uncontrollable neurological or psychiatric diseases or mental disorders, poor compliance, and being unable to cooperate and describe the treatment response. * Those who are going to undergo emergency surgery or palliative surgery due to lung abscess or hemoptysis. * Those who have been treated, or are undergoing neoadjuvant or induction radiotherapy or targeted therapy. * Those who have a combined history of other malignant tumors * Those who have a history of thoracic surgery * Those who are pregnant or breastfeeding women * Patients of childbearing age who refuse to use contraception.