Clinical Research Directory
Browse clinical research sites, groups, and studies.
Lung Function Monitoring During Hypoxemia Episodes
Sponsor: Rutgers, The State University of New Jersey
Summary
Premature infants commonly have desaturation episodes due to different reasons such as cessation of breathing or loss of lung volume. The purpose of this study is to differentiate the mechanisms of desaturation episodes with continuous lung volume monitoring. As we better understand the mechanisms underlying the desaturation episodes, newer strategies directed at underlying pathophysiology can potentially by evaluated for mitigation of these episodes.
Official title: Differentiating Pathophysiological Mechanisms of Hypoxemia Episodes by Continuous Lung Function Monitoring in Preterm Infants
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
35
Start Date
2024-04-04
Completion Date
2026-08-04
Last Updated
2024-08-02
Healthy Volunteers
No
Conditions
Interventions
Detecting changes in lung volume with hypoxemia episodes
Electrical impedance tomography (EIT) will be used to assess changes in lung aeration prior and during hypoxemia episodes to classify them into four different subtypes. FE subtype: Defined as HEs preceded by reduction in EELI below the baseline. Apnea subtype: Defined as HEs not meeting the criteria for FE subtype and preceded by cessation of breathing. Mixed subtype: Defined as HEs meeting the criteria for both FE and apnea subtypes. Unclassified: Defined as HEs not categorized into any of the above parameters.
Locations (1)
Bristol Myers Squibbs Childrens Hospital
New Brunswick, New Jersey, United States