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Decoding the Inflammasome Influence on Treatment Response in Acute Myeloid Leukemia
Sponsor: Ciceri Fabio
Summary
The study is designed as a collection of biological samples of newly diagnosed acute myeloid leukemia (AML) patients treated in the clinical units involved. Samples of peripheral blood (PB) and bone marrow (BM) will be analyzed to determine the Inflammasome profile before and after a first-line chemotherapy treatment.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2025-02-22
Completion Date
2026-08-31
Last Updated
2025-05-08
Healthy Volunteers
No
Conditions
Interventions
Clinical Practice
All the procedures in Study will be conducted as per Clinical practice for the pathology and all the samples will be collected according to ELN guidelines. There are no additional procedures but will be additionally collected up 20ml of peripheral blood and up to 15ml of Bone Marrow Aspirate at the same time of clinically indicated diagnostic procedures.
Locations (2)
GOM Bianchi Melacrino Morelli
Reggio Calabria, Calabria, Italy
IRCCS Ospedale San Raffaele
Milan, Milan, Italy