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The Impact of Music Medicine on Preterm Brain Development and Behavior
Sponsor: Brigham and Women's Hospital
Summary
The investigators are conducting a two-site randomized control trial with the aim of defining the impact of music (M) without or with parent voice (MPV) on very preterm infants' acute and cumulative stress, intranetwork connectivity on term brain MRI, and language and other neurodevelopmental outcomes at two years corrected age. This is based on the hypothesis that infants in MPV arm are expected to experience the greatest benefit compared with infants receiving standard care.
Official title: The Impact of Music Medicine on Preterm Brain Development and Behavior - A Two-Center Randomized Controlled Trial "The Lullaby Study"
Key Details
Gender
All
Age Range
24 Weeks - 30 Weeks
Study Type
INTERVENTIONAL
Enrollment
243
Start Date
2025-05-19
Completion Date
2031-03-01
Last Updated
2026-03-25
Healthy Volunteers
No
Interventions
Music
Arm 1: Music only
Music and parent voice
Arm 2: Music and parent voice
Standard Care
Standard Care
Locations (2)
Yale New Haven Hospital
New Haven, Connecticut, United States
Brigham and Women's Hospital
Boston, Massachusetts, United States