Clinical Research Directory

Inclusion Criteria: * Age 8-18 years old * Wearing corneal shape mirror more than one year and at least eight hours every night * Myopia -5.50 to -1.00 D, astigmatism \< 1.75 D, or curvature between 41.00 and 46.00D, astigmatism \< -0.75D, and best corrected visual acuity ≥1.0. * Diagnosis of dry eye: patients complained of dry eye, foreign body sensation, burning sensation, fatigue, discomfort, envy, subjective symptom such as vision fluctuation; (a) OSDI questionnaire score \>13 points, and (b) NITBUT \<10 s or (c) ocular surface dyeing assessment \> 5 corneal spots/more than nine conjunctival spots. * Participants were able to use eye drops as required, complete examinations, and return to the hospital for follow-up examinations within the specified time to complete follow-up. Exclusion Criteria: * Suffering from allergic or autoimmune disease associated with dry eye of the participants are not suitable for wearing OK lens * Pathological changes in the corneal rim * Eyelid rim lesions, cornea, uveitis, retina and other systemic diseases may affect the ocular surface. Examples include severe ocular surface diseases (Sjögren's syndrome, allergic conjunctivitis, ocular papules, conjunctival chafing, conjunctival scarring, and chemical damage); * Received any dry eye treatment within 14 days prior to the start of this study or continued use of other topical eye drops that would affect the results of the study. * Have received any other eye treatment or surgery