Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT06539468
NA

Active Surveillance for the Treatment of Low-Risk Basal Cell Carcinoma in Elderly Patients

Sponsor: University of Michigan Rogel Cancer Center

View on ClinicalTrials.gov

Summary

This clinical trial evaluates whether active surveillance (AS) is a safe and comfortable alternative to standard of care (SOC) treatment for elderly patients with low-risk basal cell carcinoma (LR-BCC). Basal cell carcinoma is a type of slow-growing skin cancer that has a very low risk of spreading inside the body (metastasis) or death. Basal cell skin cancers that are smaller across than a nickel in size and located on the trunk or limbs are particularly low risk to overall health. Active surveillance - watching and not treating unless the cancer worsens - has been shown to be a generally safe way to manage LR-BCC. Despite this, many doctors do not feel comfortable discussing this option with patients due to a lack of studies comparing it to standard of care treatment. Standard of care treatment for LR-BCC can include "scrape and burn" (electrodesiccation and curettage), surgical resection, Mohs surgery, and other approaches. These treatments can carry risks like post-operative bleeding and wound infection, and they do not always improve tumor-related quality of life. Active surveillance may be a safe and comfortable alternative to SOC treatment for elderly patients with LR-BCC.

Official title: Investigating Active Surveillance for Management of Low-Risk Basal Cell Carcinoma in the Elderly

Key Details

Gender

All

Age Range

65 Years - Any

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2024-10-08

Completion Date

2025-12-28

Last Updated

2025-04-02

Healthy Volunteers

No

Interventions

OTHER

Best Practice

Receive SOC treatment

OTHER

Educational Activity

Watch an educational video on AS for LR-BCC

OTHER

Patient Observation

Undergo active surveillance

OTHER

Survey Administration

Ancillary studies

Locations (1)

University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, United States