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Active Surveillance for the Treatment of Low-Risk Basal Cell Carcinoma in Elderly Patients
Sponsor: University of Michigan Rogel Cancer Center
Summary
This clinical trial evaluates whether active surveillance (AS) is a safe and comfortable alternative to standard of care (SOC) treatment for elderly patients with low-risk basal cell carcinoma (LR-BCC). Basal cell carcinoma is a type of slow-growing skin cancer that has a very low risk of spreading inside the body (metastasis) or death. Basal cell skin cancers that are smaller across than a nickel in size and located on the trunk or limbs are particularly low risk to overall health. Active surveillance - watching and not treating unless the cancer worsens - has been shown to be a generally safe way to manage LR-BCC. Despite this, many doctors do not feel comfortable discussing this option with patients due to a lack of studies comparing it to standard of care treatment. Standard of care treatment for LR-BCC can include "scrape and burn" (electrodesiccation and curettage), surgical resection, Mohs surgery, and other approaches. These treatments can carry risks like post-operative bleeding and wound infection, and they do not always improve tumor-related quality of life. Active surveillance may be a safe and comfortable alternative to SOC treatment for elderly patients with LR-BCC.
Official title: Investigating Active Surveillance for Management of Low-Risk Basal Cell Carcinoma in the Elderly
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2024-10-08
Completion Date
2025-12-28
Last Updated
2025-04-02
Healthy Volunteers
No
Conditions
Interventions
Best Practice
Receive SOC treatment
Educational Activity
Watch an educational video on AS for LR-BCC
Patient Observation
Undergo active surveillance
Survey Administration
Ancillary studies
Locations (1)
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, United States