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NEUROENDOCRINE REGULATION OF BONE-FAT CROSSTALK IN OBESITY
Sponsor: IRCCS San Raffaele
Summary
To study the effect of neuroendocrine dysfunctions on bone health in obesity
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
150
Start Date
2024-09
Completion Date
2025-09
Last Updated
2024-08-06
Healthy Volunteers
No
Interventions
Dexa or Biompedance analysis with clinical and biochemical evaluations
All patients will undergo body composition study with DXA or Bioimpedance analysis which are the gold standard to determine % of fat mass and fat free mass, basal biochemical examinations and oral glucose tolerance test (OGTT), and clinical evaluation with waist circumference measurement. Moreover, all patients will undergo REMS ultrasound, TBS and BSI evaluation at DXA scan and hand grip test. In addition, all patients will undergo to clinical evaluation with specific nutritional, physical activity and sleep quality questionnaire assessments and an additional volume of blood.