Clinical Research Directory

Inclusion Criteria: * Age between 18 and 60 years old; * Signed Informed Consent Form (ICF); * Participant understands and is willing to participate in the clinical study and attend visits. Exclusion Criteria: * Known history of allergy to formula components; * Have the following morbidities (or any other disease that may interfere with the study): chronic inflammatory disease, immunosuppression, diabetes, hypertension, autoimmune disease, dermatological disease in the region to be treated, acute or chronic renal failure, history of coronary disease, history of cerebrovascular disease, current neoplasia, mental illness undergoing psychiatric treatment, obesity with a BMI above 30, asthma, bronchitis, seizures, hepatitis or other active infectious diseases; * Pregnancy; * Prior filling of glutes; * Use of acetylsalicylic acid, anti-inflammatories, anticoagulants, in the fifteen days before the procedure. * Vitamin D supplementation, with normal serum levels and which you do not agree to suspend; * Use of anabolic hormones; * Vitamin D (25 hydroxyvitamin D) greater than 70 ng/mL; * Serum calcium greater than 10 mg/dL; * Patients with total body PMMA volume of 650mL or more.