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Gut Microbiota-dependent Health Impacts of Haskap Berries
Sponsor: Montana State University
Summary
Polyphenol-rich Haskap berries (Haskap) have untapped therapeutic potential to improve human health, and agricultural producers in northern U.S. states are poised to increase production if consumer demand increases. A critical knowledge gap is that little is known about the interactions between gut microbes and Haskap polyphenols to produce bioactive metabolites linked to downstream health impacts. Additionally, little is known about which Haskap varieties and harvest timing yield the greatest bioactive potential. This study aims to address these gaps by investigating the interaction of bioactive components in Haskap with gut microbiota and the resultant gut and serum metabolites, inflammation, and metabolic health, and then couple this with analysis of berries from different Haskap varieties and harvest times.
Official title: PARTNERSHIP: Elucidating Gut Microbiota-dependent Health Impacts of Haskap Berries to Inform Agricultural Production Practices That Will Maximize Bioactive Potential
Key Details
Gender
All
Age Range
35 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
120
Start Date
2025-02-26
Completion Date
2028-05
Last Updated
2025-04-02
Healthy Volunteers
Yes
Interventions
Haskap berry smoothie
A smoothie blend of berries and water
Placebo comparator
A smoothie with no polyphenolic content and matched in carbohydrate composition to the experimental haskap smoothie
Locations (1)
Montana State University
Bozeman, Montana, United States