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RECRUITING
NCT06546020
NA

Gut Microbiota-dependent Health Impacts of Haskap Berries

Sponsor: Montana State University

View on ClinicalTrials.gov

Summary

Polyphenol-rich Haskap berries (Haskap) have untapped therapeutic potential to improve human health, and agricultural producers in northern U.S. states are poised to increase production if consumer demand increases. A critical knowledge gap is that little is known about the interactions between gut microbes and Haskap polyphenols to produce bioactive metabolites linked to downstream health impacts. Additionally, little is known about which Haskap varieties and harvest timing yield the greatest bioactive potential. This study aims to address these gaps by investigating the interaction of bioactive components in Haskap with gut microbiota and the resultant gut and serum metabolites, inflammation, and metabolic health, and then couple this with analysis of berries from different Haskap varieties and harvest times.

Official title: PARTNERSHIP: Elucidating Gut Microbiota-dependent Health Impacts of Haskap Berries to Inform Agricultural Production Practices That Will Maximize Bioactive Potential

Key Details

Gender

All

Age Range

35 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

120

Start Date

2025-02-26

Completion Date

2028-05

Last Updated

2025-04-02

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

Haskap berry smoothie

A smoothie blend of berries and water

DIETARY_SUPPLEMENT

Placebo comparator

A smoothie with no polyphenolic content and matched in carbohydrate composition to the experimental haskap smoothie

Locations (1)

Montana State University

Bozeman, Montana, United States