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The Effect of Melatonin Supplementation on Cumulus Cells and IVF Outcomes
Sponsor: Kaohsiung Veterans General Hospital.
Summary
This study investigates the effects of melatonin supplementation on cumulus cell gene expression and in vitro fertilization (IVF) outcomes in women over 35 years old. In the study group, patients will receive melatonin supplementation for at least two months prior to their IVF cycles. Cumulus cells will be collected after oocyte retrieval, and IVF outcomes will be assessed.
Official title: The Effect of Melatonin Supplementation on Cumulus Cells and Reproductive Outcomes in Older Women Undergoing IVF Cycles
Key Details
Gender
FEMALE
Age Range
35 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2021-05-01
Completion Date
2025-12-31
Last Updated
2024-08-13
Healthy Volunteers
No
Conditions
Interventions
Melatonin
In the study group, patients will receive melatonin supplementation for at least two months prior to IVF cycles
Locations (1)
Department of Obstetrics and Gynecology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan
Kaohsiung City, Taiwan