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Prostate Adaptive Radiation Therapy
Sponsor: Royal North Shore Hospital
Summary
Prostate ART is a two phase study looking at using adaptive radiotherapy to help reduce toxicity for prostate cancer patients. Adaptive radiotherapy is a new technology that provides the ability to account for daily changes in anatomy. Adaptive radiotherapy also provides a foundation for which radiotherapy margins might be safely reduced. Phase 1 of this study is looking to see if a radiation therapist centred adaptive workflow can be implemented. If phase 1 of this study is safe and feasible, the study will proceed to phase 2. Part 2 of the study looks at using adaptive technology to reduce radiation treatment margins. The primary aim of this study is to see whether margin reduced treatment using adaptive radiotherapy can reduce side effects for prostate cancer patients.
Key Details
Gender
MALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
130
Start Date
2025-10-01
Completion Date
2031-10-31
Last Updated
2026-02-05
Healthy Volunteers
No
Conditions
Interventions
Adaptive radiotherapy +/- Margin Reduction
Radiotherapy using adaptive technology to recontour and replan daily as required. Reductions in the PTV margin will also be introduced in the second phase of this study.
Image guided radiotherapy
Standard radiation treatment used in the department of radiation oncology for prostate cancer
Locations (1)
Northern Sydney Cancer Centre, Royal North Shore Hospital
St Leonards, New South Wales, Australia