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Cardiotoxicity of Carbon Monoxide in Patients Treated With Hyperbaric Oxygen Therapy
Sponsor: University Hospital, Brest
Summary
Carbon monoxide poisoning is a frequent domestic accident and the leading cause of death from unintentionnal poisoning. Its toxicity is based on the CO binding to hemoglobin and myoglobin, inhibition of mitochondrial cytochrome oxidase, resulting in tissue hypoxia and reduced adenosine triphosphate synthesis and ischemia-reperfusion injury. This study aims to investigate the early and late cardiologic effects of CO in patients treated with hyperbaric oxygen (HBOT) for CO poisoning
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
66
Start Date
2022-07-25
Completion Date
2024-10-25
Last Updated
2024-08-12
Healthy Volunteers
Not specified
Conditions
Locations (1)
CHRU de Brest
Brest, France