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ACTIVE NOT RECRUITING
NCT06550895
PHASE2

A Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma

Sponsor: Janssen Research & Development, LLC

View on ClinicalTrials.gov

Summary

The purpose of this study is to define the safety of Ciltacabtagene Autoleucel (Cilta-cel) and Talquetamab in participants with high-risk multiple myeloma (MM).

Official title: A Phase 2, Open-Label, Multicenter Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

11

Start Date

2024-09-16

Completion Date

2027-08-26

Last Updated

2026-03-13

Healthy Volunteers

No

Interventions

DRUG

Cilta-cel

Cilta-cel infusion will be administered intravenously.

DRUG

Talquetamab

Talquetamab will be administered subcutaneously.

Locations (9)

University of Iowa Hospital and Clinics

Iowa City, Iowa, United States

Norton Cancer Institute

Louisville, Kentucky, United States

Barbara Ann Karmanos Cancer Institute

Detroit, Michigan, United States

Icahn School of Medicine at Mount Sinai

New York, New York, United States

University of Pennsylvania

Philadelphia, Pennsylvania, United States

Royal Prince Alfred Hospital

Camperdown, Australia

Austin Hospital

Heidelberg, Australia

Peter MacCallum Cancer Centre

Melbourne, Australia

The Alfred Hospital

Melbourne, Australia