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RECRUITING
NCT06551519

A Non-interventional Study Evaluating Clinical Utility and Implications on Improved Patient Management of Serum Neurofilament as a Prognostic Marker for Disease Activity in Patients With Relapsing Multiple Sclerosis

Sponsor: Novartis Pharmaceuticals

View on ClinicalTrials.gov

Summary

This is a prospective, multicenter, observational, non-interventional study (NIS) in patients with Multiple Sclerosis (MS) and routinely assessed serum neurofilament light (sNfL) values in Germany

Official title: A Non-interventional Study Evaluating Clinical Utility and Implications on Improved Patient Management of Serum Neurofilament as a Prognostic Marker for Disease Activity in Patients With Relapsing Multiple Sclerosis (FILAXOS)

Key Details

Gender

All

Age Range

18 Years - 99 Years

Study Type

OBSERVATIONAL

Enrollment

700

Start Date

2024-10-28

Completion Date

2028-11-29

Last Updated

2026-04-01

Healthy Volunteers

No

Interventions

OTHER

ofatumumab

This is an observational study. There is no treatment allocation. The decision to initiate ofatumumab will be based solely on clinical judgement.

OTHER

DMT category 1

This is an observational study. There is no treatment allocation. The decision to continue their current DMT will be based solely on clinical judgement.

Locations (109)

Novartis Investigative Site

Albstadt, Baden-Wurttemberg, Germany

Novartis Investigative Site

Hettingen, Baden-Wurttemberg, Germany

Novartis Investigative Site

Mannheim, Baden-Wurttemberg, Germany

Novartis Investigative Site

Schwetzingen, Baden-Wurttemberg, Germany

Novartis Investigative Site

Bamberg, Bavaria, Germany

Novartis Investigative Site

Neuburg A.d. Donau, Bavaria, Germany

Novartis Investigative Site

Regensburg, Bavaria, Germany

Novartis Investigative Site

Unterhaching, Bavaria, Germany

Novartis Investigative Site

Untermeitingen, Bavaria, Germany

Novartis Investigative Site

Weiden in Der Oberpfalz, Bavaria, Germany

Novartis Investigative Site

Wolfratshausen, Bavaria, Germany

Novartis Investigative Site

Hamburg, Hamburg, Germany

Novartis Investigative Site

Bad Homburg, Hesse, Germany

Novartis Investigative Site

Frankfurt am Main, Hesse, Germany

Novartis Investigative Site

Frankfurt am Main, Hesse, Germany

Novartis Investigative Site

Kassel, Hesse, Germany

Novartis Investigative Site

Schwalmstadt, Hesse, Germany

Novartis Investigative Site

Quakenbrück, Lower Saxony, Germany

Novartis Investigative Site

Dortmund, North Rhine-Westphalia, Germany

Novartis Investigative Site

Dortmund, North Rhine-Westphalia, Germany

Novartis Investigative Site

Gelsenkirchen, North Rhine-Westphalia, Germany

Novartis Investigative Site

Meerbusch, North Rhine-Westphalia, Germany

Novartis Investigative Site

Siegen, North Rhine-Westphalia, Germany

Novartis Investigative Site

Sundern Sauerland, North Rhine-Westphalia, Germany

Novartis Investigative Site

Chemnitz, Saxony, Germany

Novartis Investigative Site

Dresden, Saxony, Germany

Novartis Investigative Site

Görlitz, Saxony, Germany

Novartis Investigative Site

Leipzig, Saxony, Germany

Novartis Investigative Site

Leipzig, Saxony, Germany

Novartis Investigative Site

Altenburg, Thuringia, Germany

Novartis Investigative Site

Jena, Thuringia, Germany

Novartis Investigative Site

Mühlhausen, Thuringia, Germany

Novartis Investigative Site

Aalen, Germany

Novartis Investigative Site

Altenholz, Germany

Novartis Investigative Site

Alzey, Germany

Novartis Investigative Site

Aschaffenburg, Germany

Novartis Investigative Site

Augsburg, Germany

Novartis Investigative Site

Backnang, Germany

Novartis Investigative Site

Bad Krozingen, Germany

Novartis Investigative Site

Bergneustadt, Germany

Novartis Investigative Site

Berlin, Germany

Novartis Investigative Site

Berlin, Germany

Novartis Investigative Site

Berlin, Germany

Novartis Investigative Site

Berlin, Germany

Novartis Investigative Site

Berlin, Germany

Novartis Investigative Site

Berlin, Germany

Novartis Investigative Site

Bielefeld, Germany

Novartis Investigative Site

Bochum, Germany

Novartis Investigative Site

Bogen, Germany

Novartis Investigative Site

Bonn, Germany

Novartis Investigative Site

Chemnitz, Germany

Novartis Investigative Site

Coburg, Germany

Novartis Investigative Site

Crailsheim, Germany

Novartis Investigative Site

Dessau, Germany

Novartis Investigative Site

Dierdorf, Germany

Novartis Investigative Site

Dillingen Saar, Germany

Novartis Investigative Site

Dresden, Germany

Novartis Investigative Site

Duisburg, Germany

Novartis Investigative Site

Düsseldorf, Germany

Novartis Investigative Site

Düsseldorf, Germany

Novartis Investigative Site

Düsseldorf, Germany

Novartis Investigative Site

Eisleben Lutherstadt, Germany

Novartis Investigative Site

Eltville, Germany

Novartis Investigative Site

Erbach im Odenwald, Germany

Novartis Investigative Site

Erfurt, Germany

Novartis Investigative Site

Essen, Germany

Novartis Investigative Site

Essen, Germany

Novartis Investigative Site

Gelsenkirchen, Germany

Novartis Investigative Site

Gera, Germany

Novartis Investigative Site

Göttingen, Germany

Novartis Investigative Site

Hagen, Germany

Novartis Investigative Site

Hamburg, Germany

Novartis Investigative Site

Hanover, Germany

Novartis Investigative Site

Heidenheim, Germany

Novartis Investigative Site

Herford, Germany

Novartis Investigative Site

Hoppegarten, Germany

Novartis Investigative Site

Höxter, Germany

Novartis Investigative Site

Itzehoe, Germany

Novartis Investigative Site

Karlsruhe, Germany

Novartis Investigative Site

Katzenelnbogen, Germany

Novartis Investigative Site

Leipzig, Germany

Novartis Investigative Site

Lüneburg, Germany

Novartis Investigative Site

Magdeburg, Germany

Novartis Investigative Site

Magdeburg, Germany

Novartis Investigative Site

Merzig, Germany

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Minden, Germany

Novartis Investigative Site

München, Germany

Novartis Investigative Site

München, Germany

Novartis Investigative Site

Münster, Germany

Novartis Investigative Site

Neuwied, Germany

Novartis Investigative Site

Osnabrück, Germany

Novartis Investigative Site

Pforzheim, Germany

Novartis Investigative Site

Remscheid, Germany

Novartis Investigative Site

Rülzheim, Germany

Novartis Investigative Site

Salzatal, Germany

Novartis Investigative Site

Schiltach, Germany

Novartis Investigative Site

Schwäbisch Hall, Germany

Novartis Investigative Site

Siegen, Germany

Novartis Investigative Site

Singen, Germany

Novartis Investigative Site

Sinsheim, Germany

Novartis Investigative Site

Stadtroda, Germany

Novartis Investigative Site

Stuttgart, Germany

Novartis Investigative Site

Stuttgart, Germany

Novartis Investigative Site

Tirschenreuth, Germany

Novartis Investigative Site

Ulm, Germany

Novartis Investigative Site

Velbert, Germany

Novartis Investigative Site

Weil der Stadt, Germany

Novartis Investigative Site

Witten, Germany

Novartis Investigative Site

Wolfenbüttel, Germany