Clinical Research Directory

Inclusion Criteria: 1. Consent provided 2. Aged 18 to 45 years old (inclusive) 3. In good general health as evidenced by medical history, physical health and biochemistry 4. Fasting blood glucose, hemoglobin A1c (HbA1c), urea, creatinine and CRP levels within normal ranges for age. Exclusion Criteria: 1. Presence of chronic disease and/or acute illness known to affect protein/amino acid metabolism (e.g. HIV, diabetes, cancer, liver or kidney disease, neurological conditions including depression and anxiety, hypo- / hyperthyroidism, inflammatory conditions,, anemia, acute cold or flu) 2. Taking medications known to affect protein/AA metabolism (e.g. steroids, anti-inflammatory medications, acetaminophen, selective serotonin reuptake inhibitors (SSRI)) 3. Inability to tolerate the diet (i.e. allergy) 4. Significant weight loss during the past month or consumption of weight reducing diets. 5. Significant caffeine consumption (\>2 cups per day) 6. Significant consumption of alcohol (\>1 drink per day i.e. 1 beer or ½ glass of wine). 7. Unwilling to have blood drawn from a venous access or using a ventilated hood indirect calorimeter for the purposes of the study.