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Deep Versus Moderate Neuromuscular Blockade in Bariatric Surgery
Sponsor: University Hospital of Patras
Summary
The aim of this study is to investigate the effect of depth of neuromuscular blockade on the surgical field, patient postoperative pain, intestinal motility, the incidence of postoperative nausea and vomiting and the effect of deep versus moderate neuromuscular blockade on postoperative atelectasis quantitatively using chest computed tomography.This is a prospective, randomized, controlled clinical-controlled study in patients ≥18 years old scheduled to undergo elective bariatric surgery.
Official title: Deep Versus Moderate Neuromuscular Blockade in Bariatric Surgery:
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2024-08
Completion Date
2026-08
Last Updated
2024-08-14
Healthy Volunteers
No
Conditions
Interventions
Deep neuromascular blockage
maintenance of a deep neuromuscular block with rocuronium, titrated to maintain a TOF count of 0, and a PTC between 1-2. Quality of surgical field conditions' assessed by a blind surgeon as a 5 points scale(Leiden scale : 1 indicates extremely poor conditions, 2 poor conditions, 3 acceptable conditions, 4, good conditions and 5 optimal conditions)
Moderate neuromascular blockage
maintenance of a moderate neuromuscular block with rocuronium, titrated to maintain a TOF count of 1-2