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Selective Neck Dissection Versus Modified Neck Dissection in PTC
Sponsor: Fudan University
Summary
This study is a phase III, randomized controlled, open label non inferiority study. Patients who meet the inclusion criteria are randomly assigned 1:1 to either the experimental group (selective neck dissection) or the control group (modified neck dissection), with LRFS as the primary endpoint. The aim of the study is to evaluate the safety of selective neck dissection in papillary carcinoma with limited number of lymph node metastases in the lateral neck, and the quality of life compared with modified neck dissection.
Official title: Tracer Navigated Selective Neck Dissection Versus Modified Neck Dissection in Papillary Thyroid Cancer With Limited Lymph Node Metastasis in the Lateral Neck: A Randomized, Noninferiority Phase III Trial
Key Details
Gender
All
Age Range
14 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
250
Start Date
2024-11-19
Completion Date
2029-06-30
Last Updated
2026-02-27
Healthy Volunteers
No
Conditions
Interventions
Lymph node tracer navigated selective neck dissection
Selective lateral lymph node dissection (after injection of tracer, lymph nodes in compartment III-IV are dissected; if there is dyed lymph node in compartment IIA, then IIA is dissected).
Modified neck dissection
Lymph nodes in compartment IIA, IIB, III, IV, VB are dissected.
Locations (1)
Fudan Univeristy Shanghai Cancer Center
Shanghai, China