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Surgical and Pharmacological Efficacy of Knosp Grade 0-2 Prolactinoma
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Summary
The investigators carried out a multi-center comparative study, involving hospitals including the Second Affiliated Hospital of Zhejiang University School of Medicine, Peking Union Medical College Hospital, West China Hospital, Wenzhou First Hospital, and Li Huili Hospital. This study aimed to compare the efficacy of medication and surgery for specific subtypes of microadenomas and clearly defined macroadenomas (Knosp grades 0-2), in order to determine which is more effective and which has fewer benefits, thereby enhancing the evidence base.
Key Details
Gender
All
Age Range
20 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
600
Start Date
2024-10-01
Completion Date
2027-03-31
Last Updated
2024-08-15
Healthy Volunteers
No
Conditions
Interventions
Transnasal transsphenoidal pituitary lesion resection under neuroendoscopy
Transnasal transsphenoidal pituitary lesion resection under neuroendoscopy
Bromocriptin 2.5mg, 2-3 times a day
Bromocriptin 2.5mg, 2-3 times a day