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RECRUITING
NCT06558981
PHASE3

Adjuvant Radiotherapy in High Risk Locally Advanced DTC

Sponsor: Fudan University

View on ClinicalTrials.gov

Summary

This study is a phase III randomized controlled clinical trial on the role of adjuvant radiotherapy in high-risk locally advanced differentiated thyroid cancer. Patients who meet the inclusion criteria were randomly assigned 1:1 to either the experimental group (adjuvant radiotherapy+RAI) or the control group (RAI), with LRFS as the primary endpoint of the study.

Official title: The Role of Adjuvant Radiotherapy in High Risk Locally Advanced Differentiated Thyroid Cancer:a 1:1 Randomized Phase III Clinical Trial

Key Details

Gender

All

Age Range

14 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

124

Start Date

2024-07-11

Completion Date

2031-06

Last Updated

2026-02-27

Healthy Volunteers

No

Conditions

Interventions

RADIATION

Radiotherapy

Ppatients would receive external radiation therapy within 6 weeks after surgery, using intensity-modulated radiation therapy (IMRT) or volume modulated radiation therapy (VMAT) techniques. RAI would be administered as standard care. The treatment window is within 6 months after surgery.

OTHER

radioiodine treatment

RAI would be delivered based on the condition of residual lesions after surgery. The treatment window is within 6 months after surgery.

Locations (1)

Fudan Univeristy Shanghai Cancer Center

Shanghai, China