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Adjuvant Radiotherapy in High Risk Locally Advanced DTC
Sponsor: Fudan University
Summary
This study is a phase III randomized controlled clinical trial on the role of adjuvant radiotherapy in high-risk locally advanced differentiated thyroid cancer. Patients who meet the inclusion criteria were randomly assigned 1:1 to either the experimental group (adjuvant radiotherapy+RAI) or the control group (RAI), with LRFS as the primary endpoint of the study.
Official title: The Role of Adjuvant Radiotherapy in High Risk Locally Advanced Differentiated Thyroid Cancer:a 1:1 Randomized Phase III Clinical Trial
Key Details
Gender
All
Age Range
14 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
124
Start Date
2024-07-11
Completion Date
2031-06
Last Updated
2026-02-27
Healthy Volunteers
No
Conditions
Interventions
Radiotherapy
Ppatients would receive external radiation therapy within 6 weeks after surgery, using intensity-modulated radiation therapy (IMRT) or volume modulated radiation therapy (VMAT) techniques. RAI would be administered as standard care. The treatment window is within 6 months after surgery.
radioiodine treatment
RAI would be delivered based on the condition of residual lesions after surgery. The treatment window is within 6 months after surgery.
Locations (1)
Fudan Univeristy Shanghai Cancer Center
Shanghai, China