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IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia
Sponsor: University of Iowa
Summary
The purpose of this research study is to determine if the two common ways of administering additional opioids (morphine like substance, narcotic) with an epidural, either mixed in the epidural solution or given separately through the intravenous, are equally effective in controlling post-operative pain
Official title: Randomized Controlled Study Comparing the Administration of Opioids Epidurally vs IV in Patients Undergoing Laparotomy With an Epidural for Post-Operative Analgesia
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2024-09-17
Completion Date
2026-05-30
Last Updated
2025-07-16
Healthy Volunteers
No
Conditions
Interventions
Intravenous administered opioid
Hydromorphone will be received intravenously using a patient controlled administration pump, as well as patient will have a continuous bupivacaine epidural infusion
Epidural administered opioid
Hydromorphone will be added to the bupivacaine in the epidural and will have a continuous infusion along with the ability for the patient to receive epidural boluses of the medications by a patient controlled epidural administration pump
Locations (1)
University of Iowa Health Care
Iowa City, Iowa, United States