Clinical Research Directory

Inclusion Criteria: * Females aged between 18 and 60 years who are newly diagnosed with stage I, II or III breast cancer * Planned chemotherapy including an anthracycline or taxane to be completed within 6 months * Mentally capable to participate in the study and provide informed consent Exclusion Criteria: * Pre-existing female-pattern baldness resembling picture I-3 or higher on the Savin scale at baseline * History of hair transplantation, psoriasis or severe scalp infection * Undergoing or plan to receive scalp cooling * Plan for immunotherapy * Known pregnancy or lactating * Severe cardiac, hepatic, renal, pulmonary and haematic lesions or other life-threatening conditions * Use of antibiotics, probiotics or prebiotics one month prior to enrolment * No other alternative or complementary treatment for the cancer condition that may affect the gut microbiome analysis * History of allergy to probiotics or lactose * History of chemotherapy for other conditions