Clinical Research Directory

Inclusion Criteria: 1. Patients with STEMI who undergo primary PCI within 6 hours of symptom onset (Excluding prodromal symptoms) 2. Informed consent Exclusion Criteria: 1. Killip class ≥ 3 2. Chronic kidney disease with GFR \< 25 ml/min/1.73 m2 3. Pre-existing non-reversible cardiac dysfunction or heart failure 4. Current treatment with any beta blocker, RAAS inhibitor or SGLT2 inhibitor 5. Absolute or relative contraindication to any one of the study drugs that confers a risk of patient safety if the patient participates in the trial and adheres to the protocol-specified recommendations, per the assessment of the treating physician 6. Life expectancy less than one year 7. Pregnancy or women of childbearing potential who is not sterilized or is not using a medically accepted form of contraception