Clinical Research Directory

Inclusion Criteria: * Over 18 years old and under 85 years old; * Imaging examinations (MRI, CT, B-ultrasound) reveal the presence of solid masses (with a diameter \> 1 cm) within the regions accessible by endoscopic ultrasound in the pancreas, peripancreatic area, liver, adrenal gland, kidney, mediastinum, lung, and gastrointestinal submucosa. Biopsy is necessary for the diagnosis of these lesions; * Must be able to receive examinations in the research center; * Must be able to sign the informed consent. Exclusion Criteria: * Hemoglobin ≤8.0 g/dL; * Pregnant women; * Coagulation disorders (PLT \<50,000/mm3,INR \> 1.5); * Took anticoagulants such as aspirin, warfarin in the latest week; * Acute pancreatitis in the past two weeks; * inability to safely perform EUS-TA (eg, cardiorespiratory dysfunction, mental diseases, or drug addiction); refusal or inability to provide an informed consent.