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RECRUITING
NCT06565845

Analysis of Various Treatment Methods of Granulomatous Lobular Mastitis

Sponsor: First Affiliated Hospital of Harbin Medical University

View on ClinicalTrials.gov

Summary

Granulomatous lobular mastitis (GLM) is a rare benign breast disease that is difficult to distinguish from breast cancer based on clinical and imaging findings, and there is currently no standard treatment. This study aims to analyze the clinical characteristics and demographic data of GLM patients and to compare the overall effectiveness of three treatment methods: surgery alone, triple anti-tuberculosis drug therapy alone, and combined surgery with triple anti-tuberculosis drug therapy, with the goal of providing new insights for clinical treatment.

Official title: Analysis of the Clinical Characteristics and Three Treatment Methods of Granulomatous Lobular Mastitis

Key Details

Gender

FEMALE

Age Range

15 Years - 65 Years

Study Type

OBSERVATIONAL

Enrollment

350

Start Date

2024-08-19

Completion Date

2024-10-19

Last Updated

2024-08-22

Healthy Volunteers

Not specified

Interventions

PROCEDURE

Surgery

patients underwent complete excision of the inflammatory breast tissue and some surrounding normal tissue under combined intravenous with inhalation anesthesia. Damaged skin was also removed.

DRUG

triple anti-tuberculosis drug

Patients took oral rifampin (450 mg/day), isoniazid (300 mg/day), and ethambutol (15 mg/kg/day).

Locations (1)

First affiliated hospital of Harbin medical university

Harbin, Heilongjiang, China