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RECRUITING
NCT06566612

Avoidance-driven Decision Making and Learning in Anorexia Nervosa and Bulimia Nervosa

Sponsor: University of California, San Diego

View on ClinicalTrials.gov

Summary

The purpose of this study is to investigate areas of the brain responsible for avoidance learning in adults with eating disorders using brain imaging techniques, computer tasks, and self-report questionnaires and interviews. The investigators will study changes in brain activity using a procedure called functional magnetic resonance imaging (fMRI). This study will include 78 women with an eating disorder (26 with anorexia nervosa \[AN\], 26 with bulimia nervosa \[BN\]) and 26 healthy controls (HC) aged 18-39. Aim 1: Evaluate behavioral differences in active and passive avoidance learning in eating disorders and associations with symptoms. Aim 2: Evaluate whether corticostriatal and limbic-prefrontal fMRI BOLD response associated with avoidance learning differs in eating disorders relative to healthy controls and relates to symptoms. Aim 3: Evaluate whether functional connectivity of avoidance learning neural circuity differs in eating disorders relative to healthy controls.

Key Details

Gender

FEMALE

Age Range

18 Years - 39 Years

Study Type

OBSERVATIONAL

Enrollment

78

Start Date

2024-08-01

Completion Date

2027-07-31

Last Updated

2024-12-06

Healthy Volunteers

Yes

Locations (1)

UCSD Eating Disorders Treatment and Research Program

La Jolla, California, United States