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RECRUITING
NCT06567197

Multiple Sclerosis Treatment With Autologous Hematopoietic Stem Cell Transplantation in the Netherlands

Sponsor: Amsterdam UMC, location VUmc

View on ClinicalTrials.gov

Summary

The goal of this observational study is to study the long-term effects of autologous hematopoietic stem cell transplantation (aHSCT) in people with highly active relapsing-remitting multiple sclerosis. The study will evaluate the following items: 1. Disease activity 2. Safety and tolerability of aHSCT 3. Changes in the immune system Participants will be subjected to frequent visits for five years after treatment with aHSCT. During these visits, clinical testing, evaluation by questionnaires, MRI scans and blood sampling will be performed.

Official title: Multiple Sclerosis Treatment With Autologous Hematopoietic Stem Cell Transplantation (MS-ACT): A Long-term Prospective Observational Study in the Netherlands

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

OBSERVATIONAL

Enrollment

24

Start Date

2023-08-25

Completion Date

2028-09-01

Last Updated

2024-08-22

Healthy Volunteers

No

Locations (2)

Amsterdam UMC

Amsterdam, Netherlands

St. Antonius Hospital

Nieuwegein, Netherlands