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Hypofractionated Online Adaptive Radiotherapy of Breast Cancer
Sponsor: Peking Union Medical College Hospital
Summary
The goal of this clinical trial is to explore the application of online adaptive radiotherapy in patients who receive moderate hypofractionated or ultrafractionated radiotherapy after breast cancer surgery. The main questions it aims to answer are: * Can online adaptive radiotherapy improve the accuracy of dose delivery? * In patients undergoing online adaptive radiotherapy, how are the treatment-related toxicities and tumor control outcomes? Participants will Receive moderate hypofractionated radiotherapy using online adaptive radiotherapy, a dose of 43.5Gy in 15 fractions or receive ultrafractionated radiotherapy using online adaptive radiotherapy, a dose of 26Gy in 5 fractions.
Key Details
Gender
FEMALE
Age Range
35 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2024-09-01
Completion Date
2026-12
Last Updated
2026-03-20
Healthy Volunteers
No
Conditions
Interventions
Moderate hypofractionated Radiation Treatment
The online adaptive radiotherapy workflow is used to deliver radiation dose. The CTV of ipsilateral breast receives a dose of 43.5Gy in 15 fractions in patients who underwent breast conserving surgery or mastectomy.
Ultrafractionated Radiation Treatment
The online adaptive radiotherapy workflow is used to deliver radiation dose. The CTV of ipsilateral breast receives a dose of 26Gy in 5 fractions in patients who underwent breast conserving surgery or mastectomy.
Locations (1)
Peking Union Medical College Hospital
Beijing, China