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RECRUITING
NCT06568705
PHASE2

Hypofractionated Online Adaptive Radiotherapy of Breast Cancer

Sponsor: Peking Union Medical College Hospital

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to explore the application of online adaptive radiotherapy in patients who receive moderate hypofractionated or ultrafractionated radiotherapy after breast cancer surgery. The main questions it aims to answer are: * Can online adaptive radiotherapy improve the accuracy of dose delivery? * In patients undergoing online adaptive radiotherapy, how are the treatment-related toxicities and tumor control outcomes? Participants will Receive moderate hypofractionated radiotherapy using online adaptive radiotherapy, a dose of 43.5Gy in 15 fractions or receive ultrafractionated radiotherapy using online adaptive radiotherapy, a dose of 26Gy in 5 fractions.

Key Details

Gender

FEMALE

Age Range

35 Years - 70 Years

Study Type

INTERVENTIONAL

Enrollment

40

Start Date

2024-09-01

Completion Date

2026-12

Last Updated

2026-03-20

Healthy Volunteers

No

Conditions

Interventions

RADIATION

Moderate hypofractionated Radiation Treatment

The online adaptive radiotherapy workflow is used to deliver radiation dose. The CTV of ipsilateral breast receives a dose of 43.5Gy in 15 fractions in patients who underwent breast conserving surgery or mastectomy.

RADIATION

Ultrafractionated Radiation Treatment

The online adaptive radiotherapy workflow is used to deliver radiation dose. The CTV of ipsilateral breast receives a dose of 26Gy in 5 fractions in patients who underwent breast conserving surgery or mastectomy.

Locations (1)

Peking Union Medical College Hospital

Beijing, China