Clinical Research Directory

Inclusion Criteria: * \>18 years of age * Neuro-imaging confirmed non-traumatic subarachnoid hemorrhage Exclusion Criteria: * Traumatic cause of subarachnoid hemorrhage (e.g. fall, motor vehicle accident, other blunt trauma) as this is a different mechanism of hemorrhage. * Other forms of traumatic or non-traumatic intracranial bleed including intracerebral hemorrhage (ICH), subdural hemorrhage, epidural hemorrhage * Pregnancy (as the study medication, metoprolol, has FDA Pregnancy Category C rating) * Unstable vital signs not amenable to beta-1 adrenergic receptor inhibitor (B1ARi) administration including: * Systolic blood pressure \< 80 mmHg not stabilized on vasopressor medications * Heart rate \< 50 bpm associated with hypotension * Patients requiring vasopressor agents due to hypotension (SBP \<80 mmHg) * Other vital sign exclusion at the discretion of the treatment team * Previous history of severe heart failure (Stage C or D Heart Failure and/or NYHA Class III or IV) * Patient or legally authorized representative unwilling to provide informed consent