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Genetic Testing for the Prevention of Cancer in Indigenous American Communities (JUNIPER Trial)
Sponsor: Mayo Clinic
Summary
This clinical trial is studying the genetic changes in cells associated with different types of cancer in Indigenous American (IA) populations in the Southwest to improve cancer screening, precision prevention, and therapeutic intervention for individual in these communities. IA tribes have much lower rates of cancer screening, have more limited access to healthcare, are more often diagnosed at later stages of disease, and have the poorest outcomes in all types of cancer when compared to any other racial and ethnic group in the United States. Due to these significant cancer health disparities, IAs have been understudied and little is known about the molecular characterization of tumors arising in IAs. Undergoing genetic testing of tumors may improve cancer outcomes in IA participants and communities.
Official title: Journey to Understanding - Indigenous Peoples Engagement in Cancer Research Arizona (JUNIPER)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2024-09-27
Completion Date
2027-08-31
Last Updated
2026-01-29
Healthy Volunteers
No
Interventions
Biospecimen Collection
Undergo blood or saliva and leftover tissue sample collection
Communication Intervention
Receive care plan recommendations
Genetic Testing
Undergo genetic testing
Survey Administration
Ancillary studies
Locations (1)
Mayo Clinic in Arizona
Scottsdale, Arizona, United States