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NOT YET RECRUITING
NCT06570343
PHASE4

Analgesic Efficacy of Intrathecal Fentanyl-Morphine Combination Versus Morphine Alone for Intraoperative Pain During Elective Cesarean Delivery

Sponsor: Seoul National University Hospital

View on ClinicalTrials.gov

Summary

Pregnant women scheduled for elective cesarean sections under spinal anesthesia are randomly assigned to two groups: 1) the Fentanyl-Morphine (FM) group, and 2) the Morphine (M) group. In addition to 11.5 mg of bupivacaine, the FM group receives 15 μg of fentanyl and 50 μg of morphine intrathecally, while the M group receives 50 μg of morphine intrathecally. The incidence of intraoperative pain with a Numerical Rating Scale (NRS) score of 4 or higher is compared between the two groups to evaluate the analgesic effects of combined intrathecal fentanyl-morphine therapy versus morphine alone.

Official title: Analgesic Efficacy of Intrathecal Fentanyl-Morphine Combination Versus Morphine Alone for Intraoperative Pain During Elective Cesarean Delivery: a Randomized Clinical Trial

Key Details

Gender

FEMALE

Age Range

19 Years - 99 Years

Study Type

INTERVENTIONAL

Enrollment

186

Start Date

2024-09-20

Completion Date

2025-12-25

Last Updated

2024-10-01

Healthy Volunteers

Yes

Interventions

DRUG

Fentanyl-Morphine

Intrathecal injection of bupivacaine, fentanyl and morphine

DRUG

Morphine

Intrathecal injection of bupivacaine and morphine