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Analgesic Efficacy of Intrathecal Fentanyl-Morphine Combination Versus Morphine Alone for Intraoperative Pain During Elective Cesarean Delivery
Sponsor: Seoul National University Hospital
Summary
Pregnant women scheduled for elective cesarean sections under spinal anesthesia are randomly assigned to two groups: 1) the Fentanyl-Morphine (FM) group, and 2) the Morphine (M) group. In addition to 11.5 mg of bupivacaine, the FM group receives 15 μg of fentanyl and 50 μg of morphine intrathecally, while the M group receives 50 μg of morphine intrathecally. The incidence of intraoperative pain with a Numerical Rating Scale (NRS) score of 4 or higher is compared between the two groups to evaluate the analgesic effects of combined intrathecal fentanyl-morphine therapy versus morphine alone.
Official title: Analgesic Efficacy of Intrathecal Fentanyl-Morphine Combination Versus Morphine Alone for Intraoperative Pain During Elective Cesarean Delivery: a Randomized Clinical Trial
Key Details
Gender
FEMALE
Age Range
19 Years - 99 Years
Study Type
INTERVENTIONAL
Enrollment
186
Start Date
2024-09-20
Completion Date
2025-12-25
Last Updated
2024-10-01
Healthy Volunteers
Yes
Conditions
Interventions
Fentanyl-Morphine
Intrathecal injection of bupivacaine, fentanyl and morphine
Morphine
Intrathecal injection of bupivacaine and morphine