Clinical Research Directory

Inclusion Criteria: * Subject is able to verbally confirm understanding of risks, benefits and treatment alternatives of receiving the grafted ligament * Subject provides written informed consent approved by the Ethics Committee prior to any clinical investigation related procedure * Subject must agree to undergo all clinical investigation plan - required clinical follow-up visits * Subject must agree not to participate in any other clinical investigation for a period of 1 year following the procedure * Male and female subjects over 40 years old * MRI positive for full acute ACL injury * Arthrometric evaluation (KT1000) with a side-to-side difference greater than 3 mm * Symptomatic subjects with no previous knee injury * Subjects without concomitant pathologies (fracture, infections, immunodepression, HIV, HCV) that could influence the outcome of the study or prevent the subject from following the post-operative follow-up program as per protocol * I and II degree chondral lesions Exclusion Criteria: * Subjects under 40 years old * III and IV degree chondral lesions * Associated ligament injuries * Meniscus suture (e.g. hndle bucket meniscal tears) that compromise the rehabilitation program * History for sepsis * Subjects with concomitant pathologies (fracture, infections, immunodepression, HIV, HCV,) that could influence the outcome of the study or prevent the subject from following the post-operative follow-up program as per protocol * Previous knee injuries * Septic arthritis * Infected tissues * Pregnancy * Overweighed, obese subject (\>100kg) * History of metabolic bone disease * Inflammatory joint disease * Known neoplastic disease * Medical treatment (e.g steroid) * HIV positive subject * Hepatitis positive subject * Allergy to Titanium, PET, Ugurol, Gentamicin, Polystyrene Sulfonate, other medication