Clinical Research Directory

Inclusion Criteria: 1. Age 18-80 years old. 2. Glasgow Coma Scale (GCS) scores ≤8 upon admission. 3. Return of Spontaneous Circulation (ROSC) ≥30min. 4. Signed the informed consent form. Exclusion Criteria: 1. Cardiac arrest due to irreversible causes such as trauma, poisoning, etc. 2. Cardiac arrest due to end-stage conditions such as advanced cancer. 3. Persistent cardiogenic shock that is unreversed (defined as a systolic blood pressure persistently \<90mmHg despite treatment with fluid resuscitation, vasopressor agents, and inotropic medications). 4. Presence of pre-existing cerebrovascular disease prior to cardiac arrest or confirmed intracranial hemorrhage by CT scan following admission. 5. Pre-existing CPC scores of 3-5 prior to cardiac arrest. 6. Prior use of NBP or any medication containing NBP before cardiac arrest. 7. Presence of severe hepatic or renal dysfunction before cardiac arrest (defined as ≥3× upper limit of normal alanine transaminase or ≥2× upper limit of normal creatinine). 8. Bradycardia or sick sinus syndrome occurs after ROSC. 9. History of prior drug or food allergies, or known allergies to the medication components used in this study. 10. Existence of treatment limitations (patient or their legal representative refusing advanced life support treatment, including mechanical ventilation, chest compressions, targeted temperature management, etc.). 11. Presence of severe bleeding tendency upon admission. 12. Body temperature \<30℃ upon admission. 13. Pregnant or lactating women, or reproductive-age females with elevated serum human Chorionic Gonadotropin (hCG) levels. 14. Other conditions deemed unsuitable for this trial by the principal investigator.