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NOT YET RECRUITING
NCT06572722
PHASE2

Perioperative Immunotherapy for NSCLC (ECTOP-1030)

Sponsor: Fudan University

View on ClinicalTrials.gov

Summary

This trial is a randomized, multicenter, open label phase II clinical study. The main objective is to evaluate the efficacy of three perioperative immunotherapy modalities (atezolizumab adjuvant therapy, nivolumab neoadjuvant therapy, pembrolizumab neoadjuvant+adjuvant therapy) in early-stage resectable NSCLC patients. The enrolled patients are randomly assigned in a 1:1:1 ratio to receive relevant treatment in the three perioperative immunotherapy groups mentioned above, and undergoing short-term pathological efficacy evaluation and long-term prognosis follow-up after surgery.

Official title: Perioperative Immunotherapy for Early-stage Non-small-cell Lung Cancer: a Randomised, Multicentre, Open-label, Phase 2 Trial

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

200

Start Date

2024-09-01

Completion Date

2029-09-01

Last Updated

2024-08-27

Healthy Volunteers

No

Conditions

Interventions

DRUG

Atezolizumab

atezolizumab adjuvant therapy

DRUG

Nivolumab

nivolumab neoadjuvant therapy

DRUG

Pembrolizumab

pembrolizumab neoadjuvant+adjuvant therapy