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Perioperative Immunotherapy for NSCLC (ECTOP-1030)
Sponsor: Fudan University
Summary
This trial is a randomized, multicenter, open label phase II clinical study. The main objective is to evaluate the efficacy of three perioperative immunotherapy modalities (atezolizumab adjuvant therapy, nivolumab neoadjuvant therapy, pembrolizumab neoadjuvant+adjuvant therapy) in early-stage resectable NSCLC patients. The enrolled patients are randomly assigned in a 1:1:1 ratio to receive relevant treatment in the three perioperative immunotherapy groups mentioned above, and undergoing short-term pathological efficacy evaluation and long-term prognosis follow-up after surgery.
Official title: Perioperative Immunotherapy for Early-stage Non-small-cell Lung Cancer: a Randomised, Multicentre, Open-label, Phase 2 Trial
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2024-09-01
Completion Date
2029-09-01
Last Updated
2024-08-27
Healthy Volunteers
No
Conditions
Interventions
Atezolizumab
atezolizumab adjuvant therapy
Nivolumab
nivolumab neoadjuvant therapy
Pembrolizumab
pembrolizumab neoadjuvant+adjuvant therapy