Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
RECRUITING
NCT06572852

Next-Generation Endometriosis Diagnostics Through Comprehensive Multi-Dimensional Analysis

Sponsor: IRCCS San Raffaele

View on ClinicalTrials.gov

Summary

This study is a multicentric, observational, case-control, non-profit with additional procedures. It aims to deepen the understanding of the chronic gynecological conditions of endometriosis and adenomyosis, which significantly impact women's reproductive health. Its purpose is to improve early diagnosis and personalized treatment of these conditions using a multi-omic approach, that integrates genetic, epigenetic, imaging, and endometrial receptivity data. The goal is also to refine image-based predictions through recent advancements in artificial intelligence and to study uterine extracellular vesicles to assess fertility non-invasively. The study targets patients with endometriosis and/or adenomyosis and involves women seeking fertility treatments at assisted reproduction centers, who will serve as a control population. The study comprises both prospective and retrospective components. The prospective recruitment involves the collection of blood and uterine fluid samples, while the retrospective element utilizes pre-existing biobank samples for comprehensive genetic and epigenetic analysis.

Key Details

Gender

FEMALE

Age Range

18 Years - 40 Years

Study Type

OBSERVATIONAL

Enrollment

530

Start Date

2024-11-07

Completion Date

2026-08-30

Last Updated

2025-10-07

Healthy Volunteers

Yes

Interventions

OTHER

No intervention

No intervention

Locations (2)

Azienda Ospedaliero Universitaria Renato Dulbecco di Catanzaro

Catanzaro, Catanzaro, Italy

IRCCS San Raffaele Hospital

Milan, Milano, Italy