Clinical Research Directory

Inclusion Criteria: 1. Patients age must be (18 -45). 2. Patients have painful joint, clicking sound, with or without limited mouth opening. 3. patients are unresponsive to conservative treatment. 4. Patient's ability and desire to complete the treatment protocol and follow-up visits. 5. Patients with internal derangement with reduction confirmed by MRI imaging. Exclusion Criteria: 1. Patient with an inflammatory or connective tissue disease 2. Patient with previous invasive TMJ surgical procedure. 3. Neurologic disorders 4. History of injection of any substance into the target TMJ during previous 6 months. 5. History of drug allergy. 6. Patient with a history of bony or fibrous adhesion. 7. Malignant disease in the head and neck region. 8. TMJ Internal derangement without reduction. 9. Patients respond to conservative treatment. 10.Patient with a psychological problem 11.Patients having gross mechanical restrictions and condylar fracture