Clinical Research Directory

Inclusion Criteria: 1. Adult age (18-65 years old) 2. ASA（American Society of Anesthesiologists）grade I\~II 3. The estimated operation time is more than 3h, and laparoscopic abdominal surgery under general anesthesia is planned 4. BMI value 18-30kg /m2 5. Voluntary signing of informed consent Exclusion Criteria: 1. Those who have contraindications to general anesthesia or have a history of anesthesia accidents; 2. Patients with craniocerebral loss, intracranial hypertension, stroke, unstable angina pectoris, myocardial infarction; 3. Respiratory insufficiency, obstructive pulmonary disease, presence of a difficult airway, or determination of tracheal intubation difficulty (modified Markov score level III or IV) 4. uncontrolled diabetes or high blood pressure; 5. A history of drug use, alcoholism or drug dependence; 6. Abuse or long-term use of narcotic, sedative and analgesic drugs; 7. Those who are known or suspected to be allergic to or contraindicated by the process administration of various components or protocols of the study drug (sufentanil citrate injection, propofol medium/long chain fat milk, remifentanil hydrochloride for injection, and propofol disodium for injection); 8. People with a history of mental illness; 9. Participants in any drug clinical trial within 1 month before screening; 10. Pregnant and lactating women; The reluctance of fertile women or men to use contraception throughout the trial; Subjects (including male subjects) who plan to become pregnant within 3 months after the trial; 11. Subjects who have any other factors deemed unsuitable by the investigator for participation in this study.