Clinical Research Directory

Inclusion Criteria: * having a diagnosis Parkinson Disease, cerebellar ataxia, hereditairy spastic paraparesis, or a slowly progressive neuromuscular or mitochondrial disorder, confirmed by the treating physician (e.g. neurologist, rehabilitation physician) * aged 18-65 years; * being employed for at least 8 hours per week (at baseline). This also includes individuals who have reduced their working hours until reaching this threshold of 8 hours per week. Working time may be distributed across multiple working days; * having the intention to continue to work during the study period of 18 months, to prevent inclusion of participants who plan to retire within the 18-month RCT period; * being open to talk to the employer or manager about any changes or limitations in work performance (disclosing the diagnosis is not required, by law). Exclusion Criteria: * individuals who are at the beginning of a sick leave procedure (under the Gatekeeper Improvement Act; Wvp); * being fully self-employed. Partial self-employment in addition to paid employment is allowed, on the condition that the paid employment accounts for more than half of the total weekly working hours; * having a second employer for over eight hours per week; * proficiency in the Dutch language is not sufficient; * severe comorbidity or health-related event that will hamper compliance to the protocol, e.g. in case of a severe cognitive impairment, a relatively abrupt transition to a very progressive manifestation of the disease, a planned surgery.