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Sugammadex Dose Finding Under Two Years Old
Sponsor: Sang-Hwan Ji
Summary
This is a prospective dose-finding study of sugammadex for conventional reversal of rocuronium-induced neuromuscular blockade in children under two years of age. This study will explore 50% effective dose and 95% effective dose of sugammadex for reversal of neuromuscular blockade in less than two minutes under biased coin up-and-down method.
Official title: Reversal of Rocuronium-induced Neuromuscular Blockade by Sugammadex in Children Younger Than 2 Years Old: a Prospective Dose Finding Study
Key Details
Gender
All
Age Range
Any - 23 Months
Study Type
INTERVENTIONAL
Enrollment
33
Start Date
2024-09-15
Completion Date
2025-05-31
Last Updated
2024-08-29
Healthy Volunteers
No
Conditions
Interventions
Sugammadex
The starting dose of sugammadex will be 0.5mg/kg. When the dose for a patient was not effective, the dose for next patient will be increased by 0.5mg/kg. When the dose was effective, the dose for next patient will be decreased by 0.5mg/kg or maintained, with a 1:1 of allocation ratio.
Locations (1)
Seoul National University Hospital
Seoul, South Korea