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Pilot Study of RR-HNK in OCD
Sponsor: Carolyn Rodriguez
Summary
The purpose of this study is to understand how RR-HNK works in the brain to bring about a reduction in OCD symptoms.
Official title: A Double-blind, Placebo-controlled Study to Determine the Safety and Feasibility of Two Doses of Intravenous (2R, 6R)-Hydroxynorketamine (RR-HNK) in Adults With Obsessive-Compulsive Disorder
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
45
Start Date
2026-01-23
Completion Date
2029-11-30
Last Updated
2026-03-05
Healthy Volunteers
No
Conditions
Interventions
RR-HNK/Hydroxynorketamine
(2R,6R)-Hydroxynorketamine is a metabolite of the drug ketamine and a glutamate AMPA receptor antagonist.
Placebo
Sterile Saline
Locations (1)
Stanford University School of Medicine
Palo Alto, California, United States