Clinical Research Directory

Inclusion Criteria: * Age between 18 and 80 years * Recent diagnosis of ischemic stroke (from 24 hours to 5 days) . * Neurological deficit due to the stroke that affects mobility (paresis and/or ataxia) and requires motor rehabilitation. * Ability to understand and sign the informed consent form, or failing that, have sufficient support to carry out the correct follow-up of the study. Exclusion Criteria: * Moderate-severe disability prior to stroke, defined by an mRS\>2. * Unstable or severe clinical situation that prevents active rehabilitation. * Neurological deficit due to stroke that prevents walking without help from another person. The use of support with a cane, crutch or walker is permitted. * Moderate or severe dysphagia that makes therapeutic adherence difficult. * Use of creatine supplements in the last 3 months, or use of anabolic products in the last 3 months. * Severe kidney disease (GFR \<30ml/min/1.73 m2). * Musculoskeletal pathology that prevents assessment of muscle strength. For example: fractures, severe osteoarthritis, ligament tears or tendinopathies. * History of allergic reactions to creatine. * Pregnancy or breastfeeding. * Simultaneous participation in another clinical trial.