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Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
Sponsor: Duke University
Summary
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
Official title: Single-Dose Intraoperative Methadone for Pain Management in Pediatric Tonsillectomy: A Randomized Double Blind Clinical Trial
Key Details
Gender
All
Age Range
3 Years - 17 Years
Study Type
INTERVENTIONAL
Enrollment
440
Start Date
2024-11-21
Completion Date
2029-06-01
Last Updated
2025-12-05
Healthy Volunteers
Yes
Conditions
Interventions
Methadone
Single-dose intraoperative intravenous methadone with initial dose at 0.15 mg/kg in children and 0.2 mg/kg in adolescents.
Fentanyl/Hydromorphone
Per routine care, given as needed
Locations (1)
Duke University Medical Center
Durham, North Carolina, United States