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RECRUITING
NCT06577285
NA

The Effect Of Botox In Patients With Gummy Smile With And Without Zinc And Phytase Supplementation.

Sponsor: Cairo University

View on ClinicalTrials.gov

Summary

Participants with esthetic concern of excessive gingival display who meets the inclusion criteria, will be carried out including history taking, clinical examination and initial therapy. The initial therapy will consist of periodontal treatment (phase I therapy) including supragingival scaling, subgingival debridement if needed. The mechanical plaque control instructions for each patient include brushing and interdental cleaning techniques. Patients who have inadequate crown length and width ratio or short clinical crown will receive esthetic crown lengthening procedure to adjust gingival levels before being included in this study. Patients in the intervention group I will take zinc gluconate 50 mg 1 per day to increase zinc level with phytase supplement 176mg (800FTU) 2 tablets per day to give the maximum absorption of zinc, both supplements will be given for 4 days before botulinum toxin injections. Patients in the intervention group II will take zinc gluconate 50 mg 1 per day to increase zinc level, 4 days before botulinum toxin injections. Patients in the control group will receive the Botulinum toxin injections only Clinical photographs will be taken at baseline, 2 weeks, 1 month, 3 months postoperatively.

Official title: The Effect Of Botulinum Toxin A In Patients With Excessive Gingival Display With And Without Zinc And Phytase Supplementation: A Randomized Clinical Trial

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

36

Start Date

2024-06-01

Completion Date

2025-06-01

Last Updated

2024-09-23

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

zinc gluconate 50 mg with phytase supplement 176mg (800FTU)

zinc gluconate 50 mg1 per day with phytase supplement 176mg (800FTU) (Goodphyte company) 2 tablets per day

DIETARY_SUPPLEMENT

zinc gluconate 50 mg

zinc gluconate 50 mg 1 per day, 4 days before botulinum toxin injections.

Locations (1)

Faculty of Dentistry Cairo University

Cairo, Egypt