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Effects of High-intensity Exercise With Hypoxia and Taurine Supplementation on Metabolic and Mitochondrial Parameters
Sponsor: University of Sao Paulo
Summary
The prevalence of obesity in Brazil is one of the highest in Latin America. As an inflammatory disease, obesity needs to be treated, and one of the best interventions is exercise. This research aims to learn more about the effects of combining high-intensity training, recovery hypoxia, and taurine supplementation. To better understand these effects, the researchers will compare hypoxia and normoxia, as well as taurine and placebo, with all participants training in the same way. The researchers will also investigate mitochondrial respiration and food consumption to connect certain aspects of obesity with overall health.
Official title: Effects of High-intensity Intermittent Exercise With Recovery Hypoxia and Taurine Supplementation in Women With Obesity on Metabolic and Mitochondrial Parameters
Key Details
Gender
FEMALE
Age Range
25 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2025-03-01
Completion Date
2025-12
Last Updated
2025-06-04
Healthy Volunteers
Yes
Conditions
Interventions
Cycle ergometer
The initial part will last 5 minutes at low intensity, corresponding to "easy" by the RPE. The main part will be performed at the intensity of training zone 3 (100-110% of the Lan), lasting 5 minutes with a rest of 2.5 minutes between exercises. The intensity will be controlled by HR and RPE. The final part will last 3 minutes at low intensity, corresponding to "easy" by the RPE. The load progression occurred during the first four weeks, starting with 3 sets and adding 1 set per week. The intensity of each effort is 100-110%HRAnTh.
Locations (2)
University of São Paulo, School of Physical Education and Sports of Ribeirão Preto.
Ribeirão Preto, São Paulo, Brazil
University of São Paulo, School of Physical Education and Sports of Ribeirão Preto
Ribeirão Preto, São Paulo, Brazil