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The Role of a Mycobacterium Growth Inhibition Assay to Quantify Host Immune Control of M. Tuberculosis
Sponsor: Linkoeping University
Summary
The goal of this observational study is to learn about how the blood leucocytes from patients with and without exposure or disease from tuberculosis (TB) are able to kill live mycobacteria (M. tuberculosis). The main question it aims to answer is: Is intracellular growth suppression of M. tuberculosis in peripheral blood mononuclear cells variable among healthy blood donors and higher than in patients with latent TB compared to active TB?
Official title: The Role of a Mycobacterium Growth Inhibition Assay to Quantify Host Immune Control of M. Tuberculosis From Healthy Blood Donors and Patients With Latent or Active Tuberculosis.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
280
Start Date
2020-08-01
Completion Date
2025-12-01
Last Updated
2024-08-30
Healthy Volunteers
Yes
Interventions
No intervention.
Blood sampling for analysis of mycobacterial growth inhibition assay (MGIA) analysis.
Locations (2)
Kalmar County Hospital
Kalmar, Sweden
Dept of Infectious Diseases
Linköping, Sweden