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RECRUITING
NCT06580639

The Role of a Mycobacterium Growth Inhibition Assay to Quantify Host Immune Control of M. Tuberculosis

Sponsor: Linkoeping University

View on ClinicalTrials.gov

Summary

The goal of this observational study is to learn about how the blood leucocytes from patients with and without exposure or disease from tuberculosis (TB) are able to kill live mycobacteria (M. tuberculosis). The main question it aims to answer is: Is intracellular growth suppression of M. tuberculosis in peripheral blood mononuclear cells variable among healthy blood donors and higher than in patients with latent TB compared to active TB?

Official title: The Role of a Mycobacterium Growth Inhibition Assay to Quantify Host Immune Control of M. Tuberculosis From Healthy Blood Donors and Patients With Latent or Active Tuberculosis.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

280

Start Date

2020-08-01

Completion Date

2025-12-01

Last Updated

2024-08-30

Healthy Volunteers

Yes

Interventions

OTHER

No intervention.

Blood sampling for analysis of mycobacterial growth inhibition assay (MGIA) analysis.

Locations (2)

Kalmar County Hospital

Kalmar, Sweden

Dept of Infectious Diseases

Linköping, Sweden