Clinical Research Directory

Inclusion Criteria: Common to all groups: * Age superior 18 years * Patients who have received complete information about the study from an investigator and who fully consent to participate. For Parkinson Disease (PD): * Patients followed for PD diagnosed according to international criteria for the diagnosis of PD (MDS criteria), * A MoCA score greater than 20/30 * No treatment with deep brain stimulation. For REM Sleep Behavior Disorder (RBD): * Diagnosis of RBD according to ICSD-3 criteria: presence on polysomnography of an abnormal elevation of muscle tone during REM sleep (more than 18% of REM sleep without chin atonia) and/or the presence of REM sleep behaviors on video-polysomnography, * Absence of progressive neurodegenerative pathology: absence of diagnostic criteria for PD, multiple system atrophy, or Lewy body dementia. For healthy controls: \- No neurological or psychiatric disease Exclusion Criteria: Common to all groups: * Pregnant or breastfeeding women * Subjects under guardianship/conservatorship * Persons deprived of liberty.