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NOT YET RECRUITING
NCT06582186
PHASE4

Individualized First Maintenance Doses of Voriconazole Through a Multiparametric Algorithm

Sponsor: University Hospital, Grenoble

View on ClinicalTrials.gov

Summary

The goal of this interventional single-arm study is to evaluate the interest of a multiparametric algorithm for individualization of first voriconazole maintenance doses for improvement of initial voriconazole exposure in adult patients with haematological malignancies. The main objective it aims is to determine the percentage of patients with initial voriconazole trough concentrations in the therapeutic range after individualization of first maintenance doses. Participants will benefited from individualization of first voriconazole maintenance doses through a previously developed and validated multiparametric algorithm (publication in progress) taking into account CYP2C19 genotype, C reactive protein level and age.

Official title: Individualization of First Maintenance Doses of Voriconazole Using a Multiparametric Algorithm in Hematology Patients: a Prospective Single-arm Interventional Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2024-10

Completion Date

2027-10

Last Updated

2024-09-03

Healthy Volunteers

No

Interventions

DRUG

Individualization of first voriconazole maintenance doses

Individualization of first voriconazole maintenance doses

Locations (1)

Gautier-Veyret

Grenoble, France